Elanco Secures EUA for Screwworm Treatment in Livestock

INDIANAPOLIS, INDIANA, April 27, 2026

Elanco Animal Health has received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) and a Section 18 Emergency Exemption from the U.S. Environmental Protection Agency (EPA) for its products Negasunt™ Powder and Tanidil™, aimed at preventing and treating New World screwworm infestations in livestock, marking a critical step in safeguarding animal health against an emerging parasitic threat. These authorizations, issued in coordination with the U.S. Department of Agriculture (USDA), ensure that veterinarians and livestock producers are equipped with immediate, science-based solutions to respond rapidly to potential outbreaks, particularly as confirmed cases have been detected near the U.S.-Mexico border.

Emergency Authorization Strengthens Disease Preparedness

The FDA’s EUA for Negasunt Powder and EPA’s emergency exemption for Tanidil provide essential tools for early intervention against New World screwworm infestations, a serious parasitic condition caused by larvae that invade open wounds in animals. This coordinated regulatory action reflects the urgency of addressing potential outbreaks and highlights the importance of preparedness in protecting livestock populations and agricultural economies.

The products will be distributed through the U.S. Animal and Plant Health Inspection Service (APHIS) and its National Veterinary Stockpile, ensuring controlled access and proper oversight. Their use will be limited to authorized personnel, including veterinarians and trained professionals operating within designated zones, with strict compliance requirements for safety, tracking, and reporting.

These measures underscore the collaborative efforts of federal agencies to mitigate the risk of widespread infestation, reinforcing the role of regulatory frameworks in enabling rapid response to emerging animal health threats.

Targeted Solutions for Prevention and Treatment

Negasunt Powder and Tanidil are designed to prevent and treat screwworm infestations by targeting larvae in open wounds, helping to stop disease progression and reduce the risk of transmission. Early detection and prompt treatment are critical, as untreated infestations can lead to severe tissue damage, increased mortality, and rapid spread of the parasite.

Elanco also emphasizes the importance of comprehensive parasite control strategies, including the use of additional products such as Catron IV for fly and tick management. Preventing wound-causing parasites is essential, as even minor injuries can serve as entry points for screwworm larvae.

By combining treatment options with preventive measures, livestock producers can significantly reduce the risk of infestation, ensuring better animal welfare and minimizing economic losses. The availability of multiple solutions highlights Elanco’s commitment to providing integrated animal health management approaches.

Supporting Livestock Health and Industry Resilience

The emergence of New World screwworm near U.S. borders has raised concerns across the livestock industry, making proactive measures essential to prevent potential outbreaks. Elanco’s emergency-authorized products provide critical support to veterinarians and producers, enabling rapid response and effective management of infestations.

Education and vigilance remain key components of disease prevention, with experts emphasizing the importance of regular livestock monitoring, early detection of wounds, and adherence to recommended treatment protocols. These practices can help limit the spread of the parasite and protect both animal health and agricultural productivity.

From a cGxP and regulatory perspective, the emergency authorization highlights the importance of robust safety protocols, controlled distribution, and compliance with federal guidelines, ensuring that high-risk products are used appropriately and effectively. The integration of scientific innovation with regulatory oversight demonstrates how the industry can respond to urgent challenges while maintaining high standards of safety and efficacy.

Elanco’s leadership in delivering innovative solutions for animal health reinforces its role in supporting global food security and livestock sustainability, particularly in the face of emerging biological threats that require coordinated, science-driven responses.

Source: Elanco press release