WALTHAM, Massachusetts, November 5, 2026
Thermo Fisher Scientific has introduced its new Thermo Scientific AmpSure Universal SYBR Green and Probe qPCR Master Mixes, expanding its molecular biology research portfolio with affordable reagents designed to deliver reliable and reproducible quantitative polymerase chain reaction (qPCR) performance. Announced on November 5, 2026, in Waltham, Massachusetts, the new product family aims to support academic institutions, government research organizations and small biotechnology companies seeking dependable laboratory reagents while managing research expenditure. The launch addresses the growing need for cost-effective molecular biology solutions that maintain consistent experimental performance without requiring laboratories to replace their existing instruments or modify established testing procedures. The two master mixes are developed for everyday qPCR applications, allowing researchers to select detection chemistry according to their experimental requirements. By offering both SYBR Green and Probe formulations at the same price per reaction, Thermo Fisher Scientific aims to make routine molecular research more accessible and economical for laboratories working with different research budgets and experimental workflows.
SYBR Green and Probe Chemistry Support Multiple Research Applications
The newly introduced AmpSure product family consists of two qPCR master mixes designed to address different molecular research requirements. AmpSure Universal SYBR Green Master Mix is intended primarily for routine gene expression analysis, providing researchers with a suitable option for measuring changes in gene activity across different experimental conditions. Meanwhile, AmpSure Universal Probe Master Mix supports more advanced applications, including multiplexing, gene expression analysis, genotyping and microbe detection. These formulations provide laboratories with flexibility in selecting the appropriate detection chemistry based on their research objectives and assay requirements. The availability of both technologies within one product family is particularly relevant for research facilities conducting multiple types of molecular experiments. Researchers can select between dye-based SYBR Green detection and probe-based detection without having to depend on entirely different product suppliers or specialized reagent platforms. This approach is expected to support consistent qPCR workflows, experimental flexibility and efficient laboratory resource management across academic, government and biotechnology research environments.
Broad Instrument Compatibility Helps Maintain Existing Laboratory Workflows
A key feature of the AmpSure Universal qPCR Master Mixes is their broad compatibility with leading quantitative PCR instruments and commonly used laboratory reagents. Both formulations are designed to work with a wide range of reverse transcriptases, primers and probes, allowing researchers to integrate the products into their established experimental procedures. Unlike certain master mixes developed for specific instruments or highly specialized workflows, the AmpSure family focuses on universal compatibility across different laboratory systems. This flexibility may help research facilities avoid additional expenditure associated with changing equipment configurations, purchasing specialized reagents or redesigning established experimental protocols. Maintaining existing workflows is particularly important for laboratories handling multiple research projects, where consistency, reproducibility and operational efficiency directly influence experimental progress. The company also emphasizes that the products are designed to support reliable results and reproducible qPCR performance for everyday applications. Offering both SYBR Green and Probe master mixes at the same price per reaction further provides laboratories with greater flexibility when selecting reagents according to their experimental needs, without introducing different reaction-based pricing considerations.
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Commenting on the launch, Ferrier Le, Senior Manager of Research and Development at Thermo Fisher Scientific, highlighted the importance of providing dependable qPCR master mixes that meet the practical requirements of academic, government and small biotechnology research laboratories. According to the company, researchers require products that deliver reliable everyday performance while remaining compatible with the instruments and assays already available in their facilities. The AmpSure introduction reflects this requirement by combining reproducible qPCR performance, broad compatibility and value-oriented pricing within a single product family. The launch also strengthens Thermo Fisher Scientific’s portfolio of life sciences research products, supporting laboratories involved in gene expression studies, genotyping and microbial research. The company stated that the products are intended exclusively for research use and are not approved for diagnostic procedures. Pricing and availability may change depending on market conditions. Overall, the introduction of AmpSure Universal SYBR Green and Probe qPCR Master Mixes represents a continued focus on making molecular biology research more accessible while helping laboratories manage reagent costs and maintain established experimental workflows.
Source: Thermo Fisher Scientific press release
