BALTIMORE, July 17, 2026
Medifast, Inc. has announced the launch of Trilivy™, a comprehensive science-backed metabolic health system that marks the company’s strategic transformation from a traditional weight management business into a broader metabolic health company. The launch introduces Trilivy Reset Fuelings, a newly formulated line of meal replacements enhanced with MetaVantage Technology™, a proprietary ingredient platform designed to support metabolic function by targeting key metabolic pathways. The transition from the long-established OPTAVIA® brand to Trilivy reflects Medifast’s expanded focus on addressing metabolic dysfunction, a condition affecting more than 90% of U.S. adults according to cited research. By combining nutrition science, personalized coaching, behavioral support, and healthy habit formation, Trilivy is designed to help individuals improve metabolic health while supporting sustainable lifestyle changes beyond traditional weight loss programs.
Three-Phase System Targets Long-Term Metabolic Health
At the core of the new platform is Metabolic Synchronization®, Medifast’s proprietary scientific approach aimed at improving metabolic function through three primary biological objectives: Burn, Preserve, and Protect. According to company-supported clinical data, the system achieved a 14% reduction in visceral fat within 16 weeks while preserving approximately 98% of lean body mass during weight loss. The Burn phase focuses on reducing visceral fat, the metabolically active fat surrounding internal organs, while Preserve is intended to maintain muscle mass, strength, and energy throughout weight reduction. The Protect component supports healthy muscle function to promote long-term metabolic activity, efficient energy utilization, and healthy body weight maintenance. Trilivy is organized into a structured three-phase program consisting of Reset, designed to improve metabolic dysfunction; Refine, focused on enhancing metabolic flexibility and body composition; and Renew, intended to optimize long-term metabolic health and healthy aging.
MetaVantage Technology and Coaching Differentiate the Platform
Supporting the Trilivy system is the new Reset Fueling product line powered by MetaVantage Technology™, which incorporates proprietary ingredient formulations developed to support normal fat metabolism, healthy insulin function, and waist circumference reduction as part of a comprehensive metabolic health strategy. Beyond nutritional products, Medifast continues to emphasize its nationwide network of independent health coaches, whose personalized one-on-one guidance remains a central component of the company’s behavioral support model. Clinical studies cited by the company indicate that participants following the coach-supported Trilivy program achieved up to ten times greater weight loss and seventeen times greater fat loss compared with individuals attempting weight management independently. By integrating scientific nutrition, behavioral coaching, community engagement, and habit formation into a unified platform, Medifast aims to provide a more comprehensive solution for individuals seeking sustainable improvements in metabolic health.
Advertisement
Corporate Transformation Positions Medifast for Future Growth
The introduction of Trilivy represents one of the most significant strategic transformations in Medifast’s more than 45-year history, reflecting changing consumer demand for comprehensive metabolic health solutions rather than weight loss alone. The company believes growing awareness of metabolic dysfunction creates an opportunity to expand its position within the broader health and wellness market through science-driven products supported by personalized coaching and behavioral interventions. Planned commercialization of the newly formulated Trilivy Fuelings is expected to begin in August 2026, while the company continues investing in nutritional innovation and metabolic science. Although the health benefits described by Medifast remain subject to ongoing research and future consumer adoption, the launch signals the company’s long-term commitment to advancing evidence-based approaches designed to improve metabolic health, support healthy weight management, and promote lasting lifestyle transformation through an integrated wellness ecosystem.
Source:Medifast, press release
