TOKOROZAWA, Japan, June 30, 2026
Advita Ortho announced the first clinical use of its next-generation knee replacement platform in Japan, marking an important milestone in the commercialization of its integrated orthopedic technology. The platform combines the Activit-E® polyethylene bearing material within the Truliant® Knee System with the latest Advita GPS™ surgical navigation system and Newton® balancing intelligence, creating a unified workflow designed to provide surgeons with real-time information throughout total knee replacement procedures. The first surgeries were performed by Dr. Hiroshi Watanabe at Tokorozawa Hakushokai Hospital, demonstrating the platform’s ability to support personalized surgical decision-making based on individual patient anatomy and soft-tissue characteristics.
Integrated Platform Enhances Surgical Precision
The new knee replacement platform combines advanced implant materials with computer-assisted surgical technologies to improve intraoperative decision-making. The Advita GPS™ navigation system provides surgeons with continuous real-time feedback on implant positioning and alignment, while Newton® balancing intelligence assists in evaluating soft-tissue balance before final implantation. Together, these technologies enable surgeons to make informed adjustments during surgery, supporting greater procedural accuracy and a personalized approach to knee replacement. Company executives stated that integrating navigation, balancing intelligence, and implant technology into a single workflow is intended to improve surgical efficiency while helping optimize patient outcomes.
Activit-E® Polyethylene Designed for Long-Term Implant Performance
At the center of the platform is Activit-E® polyethylene technology, a highly crosslinked, vitamin E-stabilized bearing material developed through years of orthopedic materials science research. The material is engineered to deliver low wear while preserving the mechanical strength and durability required for long-term knee implant performance. According to the company, combining highly crosslinked polyethylene with vitamin E stabilization enhances oxidation resistance while maintaining toughness, supporting the longevity of knee replacement implants. The technology reflects Advita Ortho’s continued focus on advancing implant materials capable of meeting the growing demands of modern joint replacement procedures.
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Japan Launch Expands Advita’s Global Orthopedic Innovation Strategy
The first clinical use in Japan represents an important commercial milestone for Advita Ortho as it expands access to its next-generation orthopedic technologies in international markets. Company leadership noted that Japanese orthopedic surgeons have historically been early adopters of innovations that improve surgical precision and patient care. By bringing together advanced implant materials, surgeon-controlled navigation, and intelligent balancing technologies, Advita aims to provide orthopedic surgeons with a comprehensive solution that supports personalized treatment strategies while advancing the standard of care in total knee arthroplasty. The launch further strengthens the company’s position in the evolving orthopedic medical device market as demand grows for digitally enabled and precision-guided joint replacement technologies.
Source: Advita Ortho press release
